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Adequan is an FDA-approved injectable medication prescribed for the treatment of equine non-infectious degenerative joint disease (DJD), specifically in the carpal and hock joints (the equivalent of the ankle bone in humans). DJD can cause joint pain and inflammation, which can often lead to horse lameness. Lameness occurs when the horse overcompensates for the affected area, resulting in abnormal movements. Adequan can help reduce the damaging process of DJD, help reverse the loss of cartilage and encourage healthy joint function and associated lameness.
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Item Number : 157331
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Ingredients
Polysulfated Glycosaminoglycan
Recommended Dosage
Administer 1 intramuscular injection (500 mg) every 4 days for 7 treatments. Consult with your veterinarian regarding any questions on dosing.
Storage Instructions
Store at controlled room temperatures between 68° – 77°F; excursions permitted to 59° – 86°F.
**What is the FDA approved dosing regimen for Adequan?**
Confirmed by findings from a Dose Titration Study, the recommended dosage1 of Adequan is 500 mg every 4 days for 28 days intramuscularly (for a total of 7 injections).
**Why is Adequan administered every 4 days?**
Concentrations of Adequan at or near therapeutic levels were detected in the cartilage of all eight horses 96 hours post-injection.
**Are there “prophylactic” or “maintenance” dosing regimens for Adequan?**
No, upon an initial diagnosis of Degenerative Joint Disease, treatment recommendations are to initiate 500 mg every 4 days for 28 days intramuscularly. The series may be repeated as needed upon recurrence of the clinical signs of Degenerative Joint Disease and associated lameness of the carpal and hock joints.
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